1-(4-Chlorophenyl)-3-(morpholin-4-yl)urea
نویسندگان
چکیده
In the title mol-ecule, C(11)H(14)ClN(3)O(2), the morpholine ring has a chair conformation. In the crystal, pairs of mol-ecules are linked into inversion dimers by N-H⋯O hydrogen bonds.
منابع مشابه
1-[(3-Chlorophenyl)(morpholin-4-yl)methyl]naphthalen-2-ol
In the title compound, C(21)H(20)ClNO(2), the dihedral angle between the naphthyl-ene ring system and the phenyl ring is 77.86 (15)°. The morpholine ring adopts a chair conformation. The hydroxyl group is involved in intra-molecular O-H⋯N hydrogen bonding. A weak inter-molecular C-H⋯π inter-action is present in the crystal structure.
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8-Substituted 2-morpholin-4-yl-quinolin-4-ones and 9-substituted 2-morpholin-4-yl-pyrido[1,2-a]pyrimidin-4-ones with selected aryl and heteroaryl groups as the substituent have been synthesised as potential inhibitors of DNA-dependent protein kinase. A multiple-parallel approach, employing Suzuki cross-coupling methodology, was utilised in the preparation of 8-substituted 2-morpholin-4-yl-quino...
متن کامل(1R,4aS,10aR)-1,4a-Dimethyl-N-[(morpholin-4-yl)carbothioyl]-7-(propan-2-yl)-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxamide
In the title compound, C(25)H(36)N(2)O(2)S, the cyclo-hexane and morpholine rings adopt chair conformations. The cyclo-hexene and cyclo-hexane rings form a trans ring junction with the two methyl groups in axial positions. The N-H and C=O bonds in the urea group are anti to each other. The crystal structure is stabilized by inter-molecular N-H⋯O hydrogen bonds.
متن کامل(Morpholin-4-yl)[2-(morpholin-4-yl)-3,5-dinitrophenyl]methanone
In the title compound, C(15)H(18)N(4)O(7), the morpholine rings adopt chair conformations. The benzene ring forms dihedral angles of 55.94 (7) and 63.19 (7)° with the planes through the C atoms of the two morpholine rings.
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In the title compound, 0.75C12H14ClNO2·0.25C12H14ClNO, which is an adduct comprising 0.75 4-hy-droxy-piperidin-1-yl or 0.25 4-piperidin-1-yl substituents on a common (4-chloro-phen-yl)methanone component; the dihedral angles between the benzene ring and the two piperidine rings are 51.6 (3) and 89.5 (7)°, respectively. The hy-droxy-piperidine ring is in a bis-ectional oriention (bi) with the ph...
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عنوان ژورنال:
دوره 68 شماره
صفحات -
تاریخ انتشار 2012